General Structure Information
| PDB ID | 1esl |
| HGNC Gene Label(s) | SELE |
| Structure Name | insight into e-selectin(slash)ligand interaction from the crystal structure and mutagenesis of the lec(slash)egf domains |
| Resolution | 2.0Å |
| Reference | AUTH B.J.GRAVES,R.L.CROWTHER,C.CHANDRAN,J.M.RUMBERGER,AUTH 2 S.LI,K.S.HUANG,D.H.PRESKY,P.C.FAMILLETTI,AUTH 3 B.A.WOLITZKY,D.K.BURNSTITL INSIGHT INTO E-SELECTIN/LIGAND INTERACTION FROMTITL 2 THE CRYSTAL STRUCTURE AND MUTAGENESIS OF THETITL 3 LEC/EGF DOMAINS.REF NATURE V. 367 532 1994REFN ISSN 0028-0836PMID 7509040DOI 10.1038/367532A0 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 157 |
| Number Of SNVs | 38 |
| Number Of Permutations | 19839 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.078 |
| p-value | 0.674 |
COSMIC
| Number Of Residues | 157 |
| Number Of SNVs | 4 |
| Number Of Permutations | 639 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.167 |
| p-value | 0.899 |
Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC
