General Structure Information
| PDB ID | 1e4j |
| HGNC Gene Label(s) | FCGR3B |
| Structure Name | crystal structure of the soluble human fc-gamma receptor iii |
| Resolution | 2.5Å |
| Reference | AUTH P.SONDERMANN,R.HUBER,V.OOSTHUIZEN,U.JACOBTITL THE 3.2-A CRYSTAL STRUCTURE OF THE HUMAN IGG1 FCTITL 2 FRAGMENT-FC GAMMARIII COMPLEX.REF NATURE V. 406 267 2000REFN ISSN 0028-0836PMID 10917521DOI 10.1038/35018508 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 171 |
| Number Of SNVs | 25 |
| Number Of Permutations | 13348 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.263 |
| p-value | 0.015 |
ClinVar
| Number Of Residues | 171 |
| Number Of SNVs | 3 |
| Number Of Permutations | 215 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.667 |
| p-value | 0.325 |
COSMIC
| Number Of Residues | 171 |
| Number Of SNVs | 6 |
| Number Of Permutations | 2259 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.333 |
| p-value | 0.296 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 25 |
| Number Of ClinVar SNVs | 3 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.403 |
| p-value | 0.842 |
Cosmic vs. ExAC
| Number Of ExAC SNVs | 25 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | -0.107 |
| p-value | 0.84 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
COSMIC PathProx Analysis
