General Structure Information
| PDB ID | 1cvj |
| HGNC Gene Label(s) | PABPC1 |
| Structure Name | x-ray crystal structure of the poly(a)-binding protein in complex with polyadenylate rna |
| Resolution | 2.6Å |
| Reference | AUTH R.C.DEO,J.B.BONANNO,N.SONENBERG,S.K.BURLEYTITL RECOGNITION OF POLYADENYLATE RNA BY THETITL 2 POLY(A)-BINDING PROTEIN.REF CELL(CAMBRIDGE,MASS.) V. 98 835 1999REFN ISSN 0092-8674PMID 10499800DOI 10.1016/S0092-8674(00)81517-2 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 165 |
| Number Of SNVs | 10 |
| Number Of Permutations | 3291 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.022 |
| p-value | 0.165 |
COSMIC
| Number Of Residues | 165 |
| Number Of SNVs | 12 |
| Number Of Permutations | 2720 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.136 |
| p-value | 0.774 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 10 |
| Number Of COSMIC SNVs | 11 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.087 |
| p-value | 0.209 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
