General Structure Information
| PDB ID | 1cb5 |
| HGNC Gene Label(s) | BLMH |
| Structure Name | human bleomycin hydrolase. |
| Resolution | 2.59Å |
| Reference | AUTH P.A.OFARRELL,F.GONZALEZ,W.ZHENG,S.A.JOHNSTON,L.JOSHUA-TORTITL CRYSTAL STRUCTURE OF HUMAN BLEOMYCIN HYDROLASE, ATITL 2 SELF-COMPARTMENTALIZING CYSTEINE PROTEASE.REF STRUCTURE FOLD.DES. V. 7 619 1999REFN ISSN 0969-2126PMID 10404591DOI 10.1016/S0969-2126(99)80083-5 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 453 |
| Number Of SNVs | 103 |
| Number Of Permutations | 68416 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.232 |
| p-value | 0.039 |
COSMIC
| Number Of Residues | 453 |
| Number Of SNVs | 6 |
| Number Of Permutations | 641 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.4 |
| p-value | 0.556 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 103 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.41 |
| p-value | 0.056 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
