General Structure Information
| PDB ID | 1c9q |
| HGNC Gene Label(s) | XIAP |
| Structure Name | average nmr solution structure of the bir-2 domain of xiap |
| Resolution | -1.0Å |
| Reference | AUTH C.SUN,M.CAI,A.H.GUNASEKERA,R.P.MEADOWS,H.WANG,AUTH 2 J.CHEN,H.ZHANG,W.WU,N.XU,S.C.NG,S.W.FESIKTITL NMR STRUCTURE AND MUTAGENESIS OF THETITL 2 INHIBITOR-OF-APOPTOSIS PROTEIN XIAP.REF NATURE V. 401 818 1999REFN ISSN 0028-0836PMID 10548111DOI 10.1038/44617 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 117 |
| Number Of SNVs | 15 |
| Number Of Permutations | 5246 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.01 |
| p-value | 0.921 |
COSMIC
| Number Of Residues | 117 |
| Number Of SNVs | 3 |
| Number Of Permutations | 104 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.667 |
| p-value | 0.974 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 15 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | -0.533 |
| p-value | 0.572 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
