1AX8.A | LEP

General Structure Information

PDB ID 1ax8
HGNC Gene Label(s) LEP
Structure Name human obesity protein, leptin
Resolution 2.4Å
Reference AUTH F.ZHANG,M.B.BASINSKI,J.M.BEALS,S.L.BRIGGS,L.M.CHURGAY,AUTH 2 D.K.CLAWSON,R.D.DIMARCHI,T.C.FURMAN,J.E.HALE,H.M.HSIUNG,AUTH 3 B.E.SCHONER,D.P.SMITH,X.Y.ZHANG,J.P.WERY,R.W.SCHEVITZTITL CRYSTAL STRUCTURE OF THE OBESE PROTEIN LEPTIN-E100.REF NATURE V. 387 206 1997REFN ISSN 0028-0836PMID 9144295DOI 10.1038/387206A0

Variant Set Distributions

ExAC Variants

Number Of Residues 130
Number Of SNVs 21
Number Of Permutations 6762
Optimal Distance Threshold 11.0
K Statistic 0.124
p-value 0.377

Mapped Variants

[+] ExAC Missense Variants