1AH1.A | CTLA4

PDB ID	1ah1
HGNC Gene Label(s)	CTLA4
Structure Name	ctla-4, nmr, 20 structures
Resolution	-1.0Å
Reference	AUTH W.J.METZLER,J.BAJORATH,W.FENDERSON,S.Y.SHAW,K.L.CONSTANTINE,AUTH 2 J.NAEMURA,G.LEYTZE,R.J.PEACH,T.B.LAVOIE,L.MUELLER,AUTH 3 P.S.LINSLEYTITL SOLUTION STRUCTURE OF HUMAN CTLA-4 AND DELINEATION OF ATITL 2 CD80/CD86 BINDING SITE CONSERVED IN CD28.REF NAT.STRUCT.BIOL. V. 4 527 1997REFN ISSN 1072-8368PMID 9228944DOI 10.1038/NSB0797-527

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
2:204735335		V>I	A:9	(-5.59, -12.61, -3.18)
2:204735351		R>Q	A:14	(2.65, -22.50, -11.43)
2:204735378		Y>F	A:23	(-0.69, 5.22, -4.22)
2:204735390		G>D	A:27	(1.22, 14.18, -6.05)
2:204735404	rs557116456 COSM370511	V>I	A:32	(6.15, 5.72, -4.75)
2:204735405		V>A	A:32	(6.15, 5.72, -4.75)
2:204735414		T>I	A:35	(7.00, -2.65, 1.77)
2:204735435		S>I	A:42	(4.90, -16.48, 15.88)
2:204735456	rs376038796	A>V	A:49	(11.18, -3.95, -0.94)
2:204735467	rs370443546	M>V	A:53	(11.47, 5.45, -9.24)
2:204735470		M>L	A:54	(6.37, 7.41, -11.02)
2:204735505		I>M	A:67	(11.38, -15.42, -3.25)
2:204735510		T>M	A:69	(6.87, -10.50, -9.55)
2:204735525	rs144988077	G>E	A:74	(-0.22, 5.20, -11.91)
2:204735531		Q>L	A:76	(-3.70, 1.07, -9.32)
2:204735551		G>R	A:83	(4.96, -20.27, -5.33)
2:204735563		M>V	A:87	(3.92, -24.05, 4.67)
2:204735570		T>M	A:89	(-1.29, -19.47, 2.35)
2:204735583		I>M	A:93	(1.28, -6.08, 4.79)
2:204735626		I>V	A:109	(1.34, 1.22, 5.04)
2:204736110		P>L	A:122	(-3.04, -37.20, -6.79)
2:204736116		P>L	A:124	(-10.78, -38.62, -7.52)

1AH1.A | CTLA4.