1AAP.A | APP

General Structure Information

PDB ID 1aap
HGNC Gene Label(s) APP
Structure Name x-ray crystal structure of the protease inhibitor domain of alzheimers amyloid beta-protein precursor
Resolution 1.5Å
Reference AUTH T.R.HYNES,M.RANDAL,L.A.KENNEDY,C.EIGENBROT,AUTH 2 A.A.KOSSIAKOFFTITL X-RAY CRYSTAL STRUCTURE OF THE PROTEASE INHIBITORTITL 2 DOMAIN OF ALZHEIMERS AMYLOID BETA-PROTEINTITL 3 PRECURSOR.REF BIOCHEMISTRY V. 29 10018 1990REFN ISSN 0006-2960PMID 2125487DOI 10.1021/BI00495A002

Variant Set Distributions

ExAC Variants

Number Of Residues 56
Number Of SNVs 19
Number Of Permutations 913
Optimal Distance Threshold 8.0
K Statistic 0.135
p-value 0.469

Mapped Variants

[+] ExAC Missense Variants